Are you ready to quit smoking?

We are investigating a medication that may help. See if you qualify!

We're looking for volunteers who are...
- Between the age of 21-65
- Want to quit smoking cigarettes
- Willing to take study medication
- Currently smoke 10 or more cigarettes per day, but want to stop
- Able to pass a urine drug test
- Not experiencing any serious medical conditions
- Not using other tobacco products in the last 14 days

Sign-up to participate

Volunteer information will be reviewed by our team and you will be contacted for this study and your interest in future studies.

Quit Smoking Trials Lead Form

By clicking submit you agree to the Rose Research Center Terms and Conditions and that we may contact you via text, email, and/or phone unless you later withdraw your consent. Message and data rates may apply.

What is the CAST Study?

In short, it's a research study that may help you quit smoking.

The purpose of this research study we call "CAST" is to see if an investigational drug, called Centanafadine can help you quit smoking cigarettes. CAST stands for "Centanafadine as A Smoking cessation Treatment."

You will be compensated for the time related to your participation in this study. Your participation in this study will last 10 weeks and will include 6 visits to the study center.

An investigational drug is a drug that is being studied for approval by the United States Food and Drug Administration (FDA).


What are the benefits to participating in this Clinical Trial?
Gain access to new research treatments before they are widely available and potentially Quit Smoking
What are the risks to participating in a Clinical Trial?
Side effects will differ from study to study, you will be informed of any expected side effects when you come in for your first visit as well as in the consent form.
How long is the study?
Your participation in this study will last about 10 weeks and will include 6 visits to the study center.
Will I receive compensation for my participation?
Yes. If you come to all your visits and complete all your questionnaires you will earn as much as $1,175.

Additionally, we hope you may have quit smoking.
Do I need to ask my regular doctor before I can participate in a research study?
Not unless you want to.
You may want to share with them that you will be taking centanafadine to potentially help you quit smoking. Your doctor may wish to contact our study doctor (with your permission) to request additional information.
What is informed consent?
The informed consent process provides you with the information required to ensure you make an informed decision about participation in the clinical research study. This process will:

  • Help you to understand the information
  • Give you an opportunity to ask questions and to consider whether to participate
  • Obtain your voluntary agreement to participate
  • Continue to provide information as the clinical research study progresses

Before participating, we will take you through a written Informed Consent Form (ICF) that outlines the important information to consider before joining the study. The study doctor will go through this document with you and answer any questions you may have. This document provides details of the study, such as study expectations, duration, and what you will need to do. All known possible risks and potential benefits are also explained in the ICF.

After you have read and discussed all of the information about the study, you can decide whether or not to sign the consent form. This consent form is not a contract and you are always free to leave the study at any time and for any reason, with no penalty to you. Additionally, during your participation, the study doctor will let you know in a timely manner of any information that may change your mind about participating.
Why should I participate?
To help you quit smoking. According to the CDC, smoking is still the number one leading cause of preventable death in the United States.

Still interested?

Remember, this study will only require 6 visits and in 10 weeks, you may have quit smoking.
Additionally, you could earn up to $1,175 for your time and participation.

What is Clinical Research and who is Sponsoring this Study?

Clinical research is intended to advance medical and/or scientific knowledge.
The Study Sponsor is Otsuka Pharmaceutical Development & Commercialization Inc.

Ready to quit? Sign-up today!

Fill out our form below for more information. Participant information is maintained in a volunteer database system and retained for future studies as they become available. Pertinent information is confidentially kept on file to aid in selecting highly qualified candidates for research studies.

Quit Smoking Trials Lead Form

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Charlotte, NC 28262